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Professor

Office: 253 Kopchick Hall
Phone: 724-357-2368
Email: Avijita.Jain@iup.edu

Education

BS, Barkatullah University
MS, Tennessee Technological University
PhD, Virginia Tech
Postdoctoral Fellowship, Pacific Northwest National Laboratory

Field

Bioinorganic Chemistry
Organometallic Chemistry
Biochemistry

Courses

BIOC 481: Drug Design and Bioinorganic Chemistry
CHEM 101/102: College Chemistry I/II
CHEM 255: Biochemistry and Nutrition

Research Interests

My research interests revolve around development of electroactive and photoactive transition metal complexes with applications in photodynamic therapy and H₂ production. The three research projects that I am working on are:

• Design and development of tumor selective, peptide coupled organometallic photodynamic therapy (PDT) agents
• Design and development of water oxidation electrocatalysts
• Design and development of novel fluorescent sensors for monitoring protein phosphorylation

Select Publications

1. Jain, A.; Winkel, B. S. J; Brewer K. J. Photodynamic antibacterial studies on a ruthenium-based metal complex. Inorganica Chimica Acta 2022, 538, 1020996.
2. Jain A.; Garrett, N; Malone, Z. Ruthenium based photoactive metalloantibiotics. Photochemistry and Photobiology 2022, 98, 6-16.
3. Jain, A. Multifunctional heterometallic ruthenium-platinum complexes with medicinal applications Coordination Chemistry Reviews 2019, 401, 213067.
4. Davis D.; Stewart T.; Majumdar, S. Jain, A. Photoinduced Inhibition of DNA Amplification by PCR with a Photocisplatin Analog Journal of Young Investigators 2019, 37, 2, 17-21.
5. Jain, A.; Wyland K.; Hoffman, E.; Davis D.  New Ru(II)Pt(II) Bimetallic Complex: Redox, Spectroscopic, and Photoinduced Ligand Exchange Studies. Journal of Coordination Chemistry 2018, 71, 2, 231-242.
6. Wyland, K; Hoffman, E; Jain, A. DNA interaction studies and photoinduced ligand exchange kinetics of a sterically strained Ru(II) complex. Inorganica Chimica Acta 2017, 454, 229-233.
7. Hopkins, S.L.; Stepanyan, L.; Vahidi, N.; Jain A; Winkel B.S.J.; Brewer, K.J. Visible light induced antibacterial properties of Ru(II)-Pt(II) bimetallic complex. Inorganica Chimica Acta 2017, 454, 62-66.
8. Galan, B. R.; Reback, M. L.; Jain, A.; Apple, A. M.; Shaw W. J. Electrocatalytic Oxidation of formate with Nickel diphosphine dipeptide complexes: Effect of Ligands Modified with Amino Acids. Journal of Inorganic Chemistry 2013, 30, 5366-5371.
9. Buchko, G. W.; Jain, A.; Reback, M. L.; Shaw W. J. Structural characterization of the model amphipathic peptide Ac-LKKLLKLLKKLLKL-NH₂ in aqueous solution and with 2,2,2-trifluoroethanol and 1,1,1,3,3,3-hexafluoroisopropanol. J. Chem. 2013, 91, 406-413.
10. Reback, M. L.; Pangovska, B. G.; Ho, M. H.; Jain, A.; Squier, T. C; Raugei, S.; Roberts, J. A. S; Shaw, W. J.  The role of a dipeptide outer-coordination sphere on H₂-production catalysts: influence on catalytic rates and electron transfer. Chemistry A- European Journal. 2013, 19(6), 1928-1941.